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腾讯网
21 天
覃江江/程向东团队开发GPX4降解药物,触发癌细胞铁死亡
覃江江课题组前期开发了靶向GPX4的小分子抑制剂(Eur J Med Chem 2024),但因GPX4的结合口袋较浅,如经典的GPX4小分子抑制剂RSL3、ML162等,均在药代动力 ...
生物谷
6 天
Mol Cell:OPA1协调线粒体ROS和整合应激反应调控细胞铁死亡
有趣的是,OPA1在通过半胱氨酸剥夺和xGT抑制剂(erastin)导致的线粒体ROS和脂质ROS积累中发挥作用,而在通过GPx4抑制剂(RSL3)引发的ROS积累中不发挥 ...
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今日热点
Shot multiple times in Vegas
US crude prices fall
GA hand-count rule blocked
Holds rally in Georgia
Giant pandas arrive in US
Ownership stake approved
Must face US state lawsuits
Out of disaster loan money
California college shooting
Scales back discounts
People still missing in NC
Holiday sales to rise?
Revives Fox News lawsuit
Campaign denies plagiarism
Testifies before Congress
PA gun restrictions ruling
Might limit counterstrike
Revives journalist's case
Robinson sues CNN
Settles wrongful death suit
Trump Media stock plunges
Entity designated terrorists
Grants honorable discharges
USDA launches probe
Second venue in Abu Dhabi
To close 1,200 US stores
Secret Service blamed
SCOTUS rejects appeal
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