Three RIKEN researchers have shed light on the cellular mechanisms underlying chromosomal abnormalities that can cause miscarriages and congenital disorders such as Down syndrome.

Tending a garden is hard work. Imagine it from the plants' perspective. Each relies on fine-tuned genetic processes to pass ...

The well-established existence of sex differences in immune responses, including immune responses driven by T cells, cuts ...

In mammals, female (XX) and male (XY) cells exhibit sex chromosome dimorphism. To achieve dosage compensation of X-linked ...

Down Syndrome Awareness Month is recognized through October. Here's everything you need to know about the condition that ...

Delilah Ortega, 8, is a soloist in the choir at Fayetteville's School of Hope. She has also had 50 surgeries and is hard of ...

某些发育信号不仅能塑造人类胚胎，还在维持机体遗传蓝图方面发挥着重要作用，但这些信号也会阻断基因组的改变，即所谓的镶嵌现象（mosaicism）。近日，一篇发表在国际杂志 Nature Communications 上题为 “Developmental signals control chromosome segregation fidelity during pluripotency and ...

About two-thirds of people with Alzheimer’s disease are women, yet due to the challenges in studying X chromosomes, a genetic ...

Once upon a time, the Y chromosome — responsible for determining male sex — was as robust as its X counterpart. Fast forward a few million years, and it’s now a slimmed-down version of its ...

Indiana University School of Medicine researchers have identified a new genetic marker that could play a role in the ...

Typically, females have two X chromosomes (XX), and males have one X and one Y (XY). However, some males have an additional X chromosome (XXY), and some females have an extra X too (XXX). The ...

Chromosome rearrangements caused by chromothripsis occur in 30%-40% of all cancers and are commonly found in aggressive tumors such as sarcomas, glioblastomas, and pancreatic cancer. Chromothripsis ...