Objective: The aim of this study was to compare the antihypertensive efficacy and tolerability of the calcium channel antagonist amlodipine besylate versus the angiotensin II type 1 receptor ...

The calcium channel blocker amlodipine and angiotensin ll receptor blocker losartan, with or without hydrochlorothiazide (HCTZ), were compared for the treatment of mild to moderate hypertension in ...

Phase III trial results of novel triple combination pill for hypertension published in The Lancet Novel combination pill ...

Authors randomly allocated 1,385 participants to four groups --- 551 to GMRx2, 276 to telmisartan–indapamide, 282 to telmisartan–amlodipine, and 276 to amlodipine–indapamide groups ...

Because the FDA does not require any understanding of the mechanism by which a drug acts, it could be tempting to move into clinical trials without this knowledge. However, this may set the stage ...

In the latest in our monthly series, Dr James Chambers asked readers to suggest what was causing ongoing nausea and tingling ...

The defects in molecular and cellular processes that constitute the triggers of specific pathologies are referred to as mechanisms of disease. Research in this area is vital for designing ...