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腾讯网
21 天
覃江江/程向东团队开发GPX4降解药物,触发癌细胞铁死亡
覃江江课题组前期开发了靶向GPX4的小分子抑制剂(Eur J Med Chem 2024),但因GPX4的结合口袋较浅,如经典的GPX4小分子抑制剂RSL3、ML162等,均在药代动力 ...
生物谷
6 天
Mol Cell:OPA1协调线粒体ROS和整合应激反应调控细胞铁死亡
有趣的是,OPA1在通过半胱氨酸剥夺和xGT抑制剂(erastin)导致的线粒体ROS和脂质ROS积累中发挥作用,而在通过GPx4抑制剂(RSL3)引发的ROS积累中不发挥 ...
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今日热点
Trump Media stock plunges
Campaign denies plagiarism
Shot multiple times in Vegas
Testifies before Congress
GA hand-count rule blocked
PA gun restrictions ruling
Might limit counterstrike
Grants honorable discharges
Secret Service blamed
USDA launches probe
US crude prices fall
Must face US state lawsuits
US adults loneliness survey
Revives journalist's case
Out of disaster loan money
Holiday sales to rise?
Ownership stake approved
Robinson sues CNN
Entity designated terrorists
Settles wrongful death suit
Broadband data caps probe
US Navy aircraft crashes
Revives Fox News lawsuit
$750M US chips grant
Salton Sea conservation
Second venue in Abu Dhabi
SCOTUS rejects appeal
$1.4B renovation deal OK'd
TX Senate debate takeaways
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