(B) CDK1 and CDK2 bind to multiple cyclins (cyclin types A, B, D and E), whereas CDK4 and CDK6 only partner D-type cyclins. Thick lines represent the preferred pairing for each kinase. (C ...
The study, published in The EMBO Journal 2024, highlights two critical proteins: Cyclin-dependent kinase 1 (CDK1) and TDP1, both of which play significant roles in cancer cell DNA repair. According to ...