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The genetic underpinnings of early-onset Alzheimer’s disease began to emerge in 1987. However, genetic risk factors for the vastly more common late-onset cases were not uncovered until 1993 ...

Adult-onset leukodystrophies and genetic leukoencephalopathies comprise a diverse group of neurodegenerative disorders of white matter with a wide age of onset and phenotypic spectrum. Patients with ...

Setting 194 sites; 16 countries. Participants Subjects with T2D (n=1199) exposed to treatment. Interventions Semaglutide 0.5 mg versus dulaglutide 0.75 mg (low-dose comparison); semaglutide 1.0 mg ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Hypoglycemia triggers autonomic and endocrine ...

GDM is defined as carbohydrate intolerance of variable severity with onset or first recognition during pregnancy. It has been demonstrated that good metabolic control maintained throughout ...

The drugs they compared included metformin, a widely used first-line treatment for diabetes; insulin glargine and short ... starting the medication and the onset of the infection varied widely ...