Objective: We previously found that male (M), but not female (F), Sprague-Dawley (SD) rats develop age-dependent hypertension (HTN) that is associated with cognitive impairment. We hypothesized that ...
We hypothesized that the diurnal control of BP and natriuresis is impaired in aged male Sprague Dawley (SD) rats and may be associated with altered kidney expression of circadian clock gene proteins.
The manifestation of toxicity in Sprague-Dawley rats, including changes in weight and behavior, served as Injury Phenotype Evidence (IPE). To determine Adverse Outcomes Evidence (AOE), the hearts of ...
Finally, the potential mechanisms of action were further validated using western blot and real-time quantitative RT-PCR analysis. Male Sprague-Dawley rats (220–250 g) were sourced from CHENGDU DOSSY ...
In this commentary, we describe the current status of the rat genome sequence and the ... data extends to one-fold coverage of the Sprague-Dawley (SD) genome completed by Applied Biosystems ...