Liver glucose metabolism in humans - PMC - National Center for ...
网页2016年11月29日 · Both gluconeogenesis and glycogenolysis contribute to hepatic glucose production. During short-term periods of fasting, glycogenolysis is the predominant source of glucose released to the bloodstream.
Molecular Pathophysiology of Hepatic Glucose Production
网页A key mode of control over hepatic glucose production is that of net glycolytic/gluconeogenic flux. By regulating the activity of key glycolytic or gluconeogenic enzymes, the liver can switch from net hepatic glucose storage to glucose output.
Regulation of hepatic glucose metabolism in health and disease
网页2017年7月21日 · Net hepatic glucose production is the summation of glucose fluxes from gluconeogenesis, glycogenolysis, glycogen synthesis, glycolysis and other pathways. In this Review, we discuss the...
The Liver & Blood Sugar - Diabetes Education Online
网页The liver supplies sugar or glucose by turning glycogen into glucose in a process called glycogenolysis. The liver also can manufacture necessary sugar or glucose by harvesting amino acids, waste products and fat byproducts.
Hepatic glucose metabolism in the steatotic liver - Nature
网页2024年2月2日 · This Review provides a comprehensive overview of glucose metabolism in steatotic liver disease (SLD) and obesity, describes new techniques for hepatic glucose flux assessment and discusses...
Molecular pathophysiology of hepatic glucose production
网页Aberrant regulation of hepatic glucose production (HGP) can result in deleterious clinical outcomes, and excessive HGP is a major contributor to the hyperglycemia observed in Type 2 diabetes mellitus (T2DM).
Glucose Metabolism and Regulation: Beyond Insulin and …
网页2004年7月1日 · Glucose appearance is a function of hepatic(endogenous) glucose production and meal-derived sources and is regulated by pancreatic and gut hormones. Glucose disappearance is insulin mediated. Calculated from data in …
Hormonal regulation of hepatic glucose production in health …
网页2011年7月6日 · We review mechanisms that regulate production of glucose by the liver, focusing on areas of budding consensus, and endeavoring to provide a candid assessment of lingering controversies.
How the Liver Affects Blood Glucose Levels – Diabetes Daily
网页2023年6月19日 · In addition, the rise in glucose and insulin caused by glucose ingestion inhibits endogenous hepatic glucose production, which serves to minimize postprandial elevations in blood glucose.
Unraveling the Regulation of Hepatic Gluconeogenesis
网页2019年1月24日 · Hepatic gluconeogenesis, de novo glucose synthesis from available precursors, plays a crucial role in maintaining glucose homeostasis to meet energy demands during prolonged starvation in animals. The abnormally increased rate of hepatic gluconeogenesis contributes to hyperglycemia in diabetes.
- 某些结果已被删除