Sprague Dawley Rat - an overview | ScienceDirect Topics
2.2.2 Sprague–Dawley (SD) rat. As an outbred one, the SD rat strain was also obtained from Wistar rat, and used extensively in medical research, including applications in toxicology, pathology, neurobiology, oncology (Harleman et al., 2012; Popovich et al., 1997), characterized by docile nature, high productivity, and low incidence of ...
Sprague Dawley® | Taconic Biosciences
Opportunist Free (OF) SD rats are useful as health sentinels, clean fosters or where co-housed with immunodeficient/genetically modified models. The Sprague Dawley® outbred model was developed by Sprague Dawley, Inc. NIH received stock from Sprague Dawley, Inc in 1945.
CD® IGS (Sprague Dawley) Rats | Charles River - Charles River …
CD® IGS (Sprague Dawley) Rats. Originated in 1925 by Robert W. Dawley from a hybrid hooded male and a female Wistar rat. To Charles River in 1950 from Sprague Dawley, Inc. In 1991, 8 colonies were selected to form the IGS Foundation Colony.
Sprague Dawley Rat - an overview | ScienceDirect Topics
Sprague Dawley (SD) rats are an outbred stock originally developed from Wistar rats crossed with a variety of other laboratory and wild rats. From: Haschek and Rousseaux's Handbook of Toxicologic Pathology (Fourth Edition), 2022
Genetic characterization of outbred Sprague Dawley rats and …
2022年5月31日 · Sprague Dawley (SD) rats are among the most widely used outbred laboratory rat populations. Despite this, the genetic characteristics of SD rats have not been clearly described, and SD rats are rarely used for experiments …
Laboratory rat - Wikipedia
The albino laboratory rat with its red eyes and white fur is an iconic model organism for scientific research in a variety of fields. Laboratory rats or lab rats are strains of the rat subspecies Rattus norvegicus domestica (Domestic Norwegian rat) which are bred and kept for scientific research.
Sprague Dawley Rat - an overview | ScienceDirect Topics
The SDT rat is an inbred strain of Sprague-Dawley rat that has been established as a nonobese model of type 2 diabetes (Sasase et al., 2013). Male SDT rats show high plasma glucose levels by 20 weeks of age with pancreatic islet histopathology.
Comparative analysis of growth characteristics of Sprague Dawley rats ...
2015年12月22日 · The Sprague-Dawley (SD) is an outbred rat, first generated by Robert S. Dawley during the 1920s by breeding Wistar rats to hybrids of laboratory derived and wild stocks. In 1950, Charles River Laboratories (CRL) acquired a breeding stock and developed a new line with better microbial status by caesarian derivation [ 22 ].
Historical Control Background Incidence of Spontaneous …
2024年1月28日 · This information provides a reference for the types, incidence, and range of background neoplastic findings that occur in SD rats, providing an important reference to toxicologic pathologists evaluating two-year carcinogenicity studies.
Genetic characterization of outbred Sprague Dawley rats and
2022年5月31日 · Sprague Dawley (SD) rats are among the most widely used outbred laboratory rat populations. Despite this, the genetic characteristics of SD rats have not been clearly described, and SD rats are rarely used for experiments …